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Can THC Help Some Schizophrenics?

By Bruce Mirken, Marijuana Policy Project. Posted June 5, 2009.


Report cites "grossly psychotic, assaultive," schizophrenic "became calm, logical, nonviolent and cooperative within days" after taking THC.

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The surprising finding that THC might help at least a small percentage of schizophrenia patients for whom conventional treatments have failed was reported in the June issue of the Journal of Clinical Psychopharmacology.

This is surprising because, as the British government’s Advisory Council on the Misuse of Drugs reported last year, "there is clear evidence that the use of cannabis may worsen the symptoms of schizophrenia and lead to relapse." The ACMD -- a far more objective body than any U.S. government outfit remotely connected to drug policy -- did not consider marijuana to be a significant cause of psychosis in otherwise healthy people; its report reflects a broad consensus that marijuana (and specifically THC) can worsen the prognosis of schizophrenics or those with a genetic vulnerability to schizophrenia.

But doctors at the Rockland Psychiatric Center in Orangeburg, N.Y., reviewing the records of one severely ill patient -- a man who was "grossly psychotic, assaultive, disorganized" and not responding to conventional treatment -- noticed that he had a history of "calm behavior when he was using marijuana." So as an experiment, they prescribed THC capsules (dronabinol, brand name Marinol).

"Remarkably," they write, "he became calm, logical, nonviolent, and cooperative within days and was discharged within weeks."

They then tried the same thing with five other patients with a similar history -- unresponsive to conventional treatments but showing some signs of improvement when they smoked marijuana. Three of these "improved to a clinically significant extent," one showed no significant change, and one got somewhat worse. That’s a remarkable level of success in chronically ill patients for whom conventional anti-psychotic drugs had failed, "in which success with any intervention might be unlikely."

The article goes on to lay out some possible explanations, but at this point no one knows for sure why this small group of psychotic patients had an anomalous and positive reaction to THC. What is clear is that the relationship of cannabinoids to schizophrenia is more complex and variable than even many experts -- much less anti-marijuana propagandists – have acknowledged.


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See more stories tagged with: marijuana, schizophrenia, thc

Bruce Mirken is communications director for the Marijuana Policy Project.

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Bruce.... Please
Posted by: xxdr_zombiexx on Jun 6, 2009 3:44 AM   
Current rating: 5    [1 = poor; 5 = excellent]
Referring to people as "schizophrenics" is more or less rude these days. Insensitive.

The label reduces the person to a stereotype.

It's "people or persons with schizophrenia".

I am a licensed mental health professional and have had this conversation 4 times in the last week and a half.

Thanks!

Doc

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» RE: Bruce.... Please Posted by: Wendy Benay
Now....
Posted by: xxdr_zombiexx on Jun 6, 2009 3:48 AM   
Current rating: 5    [1 = poor; 5 = excellent]
Cannabis/thc does have an undesirable effect on many people with mood disorders (Schizophrenia, biploar, major depression) but not all people.

it's roulette.

Great to see that some people CAN benefit from THC tx for this! Easy to grasp, actually.

Some meds work one way for some people, another way for others.

Medical marijuana will not work for everybody but it does work for some - possibly a large number of people.

We'll never know as long a proper research is banned and thwarted.

Plain & Simple.

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» RE: Now.... Posted by: Wendy Benay
Previous study was misinterpreted.
Posted by: teleomorph on Jun 8, 2009 10:48 AM   
Current rating: 5    [1 = poor; 5 = excellent]
Indeed, the previous study showing a link between cannabis use and schizophrenia supports the recent findings that it is actually a treatment. It was a classic case of causal misinterpretation. What they really uncovered was the fact that people suffering symptoms of schizophrenia showed a tendency SELF-MEDICATE with cannabis.

[Animals in the wild innately know how to treat their ailments with specific medicinal plants (zoopharmacognosy) and humans can do this too.]

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LOCALLY WE HAD A 2500 BED FACILITY IN 1960. SINCE THEN THE REPUBLICANS
Posted by: Raymond Emerson on Jun 8, 2009 1:31 PM   
Current rating: 5    [1 = poor; 5 = excellent]
cured two thousand of them and put them out on the streets. In the past the money to fund this came from the state. These people have been put on SSI. The money now comes from your Social Security contributions. You had a hidden tax increase.

Of those that have been cured I think of one fellow that has "anxiety attacks". You guys may all have new nomenclature for this by now. A policeman was sent, off duty, as a debt collector and he punched him out. So he is on SSI. On the streets it is called a "nut check". He gets 675 dollars a month and pays 350 rent for a room. He smokes like a freight train. Almost all of the institutionalized mentally ill do. A few "persons with schizophrenia" are so afflicted that they cannot. The new super taxes on tobacco are driving him wild. A pound of tobacco that could have been had for 12.50 is now 63.50. He eats at the soup kitchen and shows up for all versions of the food pantries. The loan sharks are into him for more than he can repay. Its only a matter of time before there is another "run in" with the law because of an uncontrolled anxiety attack. Some years ago he went to the local "mental health" clinic with a full blown anxiety attack. They had him jailed. He never went back. Cannabis is a complete blocker for his anxiety. He is in trouble. He is not going to get any help.

I know a young, 40ish, black woman who is on SSI and is a republican cure. She walks the streets. She will dress as a male for protection. She talks to the walls. They answer. She goes into catatonic stages and does not speak for a week at a time. She most probably is not a danger to anyone except herself. She is on no medications. She will not go back to any doctors because they "zombied her out". She has severe sensory hallicinations. Sometimes she itches all over. The general public mistakes it for lice or a skin ailment. She keeps her head shaved. Its not lice. A couple of joints and she dances and sings and plays the fool. But it is the only pleasant time she ever has.

I am told that the big drug companies have 26 different THC drugs under developement. Is this a true statement? I have no idea. If it is true do these guys know something we don't?

My wife has Lupus and fibromyalgia. She is in pain 24 hours a day. I know that a morphine injection will give her complete relief. There seems nothing for long term pain relief. THC may well be it. It certainly does deserve a good testing.

I knew one fellow on Dr. prescribed THC to try to slow up his epileptic seizures. The idea was that if the seizures could be controlled he could work as a fry cook. He was too laid back to "fry cook".

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» I work for an ACT Team in Atlanta Posted by: xxdr_zombiexx
vote to leaglize
Posted by: sopomike on Jun 8, 2009 2:24 PM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
dial 1-973-409-3274 when 1 million calls have been made it will be given to the president .

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» thanks for the number Posted by: Grandma Crabby
Cannabis
Posted by: Jaffe on Jun 10, 2009 10:39 AM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
Cannabis has also proven effective in lowering the interocular pressure of glaucoma sufferers, who otherwise have to put up with extraordinarily toxic eye drops or surgery which is not conclusive-- that is, it has to be repeated.

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Possible Explanation?
Posted by: bornxeyed on Jun 11, 2009 3:28 PM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
The article goes on to lay out some possible explanations, but at this point no one knows for sure why this small group of psychotic patients had an anomalous and positive reaction to THC.

Perhaps they weren't truly psychotic?

The schizophrenics I have had the oppurtunity to know, to a one, DO NOT like ths effects of marijuana.

Maybe this is a litmus test for schizophrenia?

The neurological symptoms I have presented since being prescribe Cipro, if listed out and handed to a group of psychiatrists, would surely be, by some, diagnosed as schizophrenic.

But I'm not. I can't give a blanket term for the condition, but it is NOT schizophrenia - it would be more likened to the organic damage from pesticides, or over-excitation "neurosis".

And while I don't exhibit psychoses now, it is more like chronic fatigue syndrome, fibromyalgia, ADHD and anxiety disorders, in the first 6 months I could easily have been diagnosed as psychotic, autistic, mild catatonia, early-onset senility etc, depending on which Dr. paid attention to what symptoms.

Anti-psychotic drugs surely don't help - any who have tried them for this condition have gotten worse. I refused any that were offered.

"Sorry Doc, I'm not trying klonopin after some damn antibiotic damnaged my nervous system>"

But marijuana helps! Not just helps, it makes me feel "normal", as I did bfore I was poisoned, but stoned. I really regret I didn't have access to any for a year before the poisoning and for a year after.

It's occurred to me, had I been smoking regularly during that period I might not have had such profound damage.

Perhaps theese patients are similarly misdioagnosed?

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all we put in our body affects the body mind spirit complex
Posted by: caru on Jun 14, 2009 9:49 AM   
Current rating: 5    [1 = poor; 5 = excellent]
hey hey hey -- now i personally have zero respect for 99% of the modern mental health care approaches on this planet. i got to this high number because some of these folks approve TORTURE, right, and they consider themselves medical professionals. a medical professional does not equal healer.

as far as big pharma -- all the meds that they serve up corrupt the spirit -- including giving meds to depressed people and the same meds make them off themselves. again, good going there -- greed supercedes life.

herbalists have been hunted by people in power since, when, the church came into power? so there too, the church is another institution that has zero cred with me. the church has banished our birth right, oneness with life.

the herbailsts, the indigenous, those connected to the spirit of the planet and the beings of the garden and devas of the forest, these herbalists are working with sometimes 10,000 years of knowledge and evolution. these are the only ones to trust. western medicine is good for cutting things out or fixing mechanics but as a whole knows little of anything else. they are so after the fact too. you know.

the yogis, through the simple process of self inquiry have been engaged in self healing of the complete body mind spirit complex for perhaps 10,000 years too. passing the learning from one to another.

in an alienated society with an alienated health community and an alienated system of political control what can we expect but the fact that even though 'we've got to ourselves get back to the garden' we are stymied at every turn. the garden of eden is here on earth now. all the health is here for us -- nothing new really -- just connection, just immersion and just presence, voila restoration.

i am sorry for anyone who uses the terms the mental health industry throws out there including the s word (look at any dsmv and you will be sorry too). i have studied this illness and i know it is a catch all for some maybe 1000s of di eases -- people can only describe what they see on the outer with one grossly misinterpreted word. the same health care professionals have no idea how to restore the being.

everything we put in our mouth becomes who we are until portions are eliminated. who are we? we are a country of hypoglycemic, carbo-building, alchoholic, adhd people full of the toxins of the previous 500 years. do not doubt that our processed food choices and the toxic planet corrupts our genetic makeup within our lifetime. it is all a matter of how many vectors we cross.

now for my personal story. two women. one gets thrown into mental health system at 17. the other escapes her parents efforts to institutionalize her, she goes rainbow. in the rainbow there is guidance. in our mental health system, only slicing and dicing. now the women are 30s-40s. the rainbow woman has her mind and body and spirit. the other has had her mind taken from her almost entirely, voila zombie. she was a vibrant exciting human, no more. thanks to big pharma. we trust this system even though it has no answers and advocates torture and zombie humans.

i chose restoration for all of these folks. all life. guidance and connectivity for us. deep ecology, deeep earth wisdom. healing on all levels: body mind spirit.

the mother earth gives medicine so freely. just go within, inquire and all is revealed.

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