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Health & Wellness

Big Pharma Bribes Doctors to Hook Your Kids on Drugs

By Bruce E. Levine, AlterNet. Posted July 17, 2009.


Americans must start to question the legitimacy of the exploitative pharmaceutical-industrial complex and the predatory people atop them.
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"The wave of evil washes all our institutions alike." –Ralph Waldo Emerson

The wave of evil washes not only the financial-industrial complex, the military-industrial complex, the energy-industrial complex, and predatory executives at AIG, Citibank, Halliburton, Blackwater/Xe, Enron, and Exxon. The pharmaceutical-industrial complex has virtually annexed the mental health profession, whose all-star opportunist team is captained by Harvard psychiatrist Joseph Biederman, the high-profile doctor most responsible for the explosion of kids on psychiatric drugs, first for attention deficit hyperactivity disorder (ADHD) and then for bipolar disorder.

In 2008, Biederman was nailed by Congressional investigators for taking $1.6 million from drug makers from 2000 to 2007 and failing to report most of this loot to his university, a major conflict of interest in violation of the rules. In a February 26, 2009 deposition given by Biederman to several states attorneys (who were claiming that makers of antipsychotic drugs defrauded state Medicaid programs by improperly marketing their medicines), Biederman was asked what rank he held at Harvard.

"Full professor," Biederman answered.

"What’s after that?" asked one state attorney, Fletch Trammell.

"God," Biederman responded.

"Did you say God?" Trammell asked.

"Yeah," Biederman said.

As part of this legal proceeding, Biederman was forced to provide documents relating to his interactions with Johnson & Johnson, the giant pharmaceutical company. These documents included presentations he made over several years summarizing the work of his center financed by Johnson & Johnson. On March 20, 2009, the New York Times reported that Biederman pitched Johnson & Johnson that his proposed research studies on its antipsychotic drug Risperdal would turn out favorably for Johnson & Johnson -- and then Biederman delivered the goods. The Times also reported that in 2005 Biederman proposed a study on adolescents using the ADHD-drug Concerta, manufactured by Johnson & Johnson, and he assured the company that his study would "extend to adolescents positive findings with Concerta." And in 2006, Biederman was co-author of a study showing that children given Concerta for a prolonged period did not have reduced growth, allaying a significant concern about the medicine -- but in contradiction to what has now been established.

For decades, the majority of American doctors, mental health professionals, the media, and the general public have yielded to the disseminations of Harvard psychiatrist Joseph Biedeman who successfully evangelized for more children -- and younger children -- to be medicated with powerful psychiatric drugs.

The blowback from ADHD drugs is reported in the current July 2009 Scientific American Mind article "Do ADHD Drugs Take a Toll on the Brain?" a comprehensive report of the long-term dangers of ADHD drugs such as Ritalin, Concerta, Adderall, and Vyvanse.

The Centers for Disease Control (CDC) estimated in 2005 that 9% of boys and 4% of girls in the U.S. were taking ADHD stimulant medications; and according to a 2007 study, ADHD-drug prescriptions rose by almost 12 percent a year between 2000 and 2005.

ADHD drugs are either the "amphetamine-like" methylphenidate (e.g., Ritalin and Concerta) or actual amphetamines (e.g., Adderall and Vyvanse), so it should not be surprising that long-term use is associated with many hazards. The current Scientific American Mind piece, authored by Edmund S. Higgins, clinical associate professor of family medicine and psychiatry at the Medical University of South Carolina states, "Methylphenidate has a chemical structure similar to that of cocaine and acts on the brain in a very similar way." In February 2009, neuroscientists at the Rockefeller University reported cocaine-like structural and chemical alterations in the brains of mice given methylphenidate.


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See more stories tagged with: drugs, big pharma, adhd, amphetamines, joseph biederman

Bruce E. Levine, Ph.D., is a clinical psychologist and author of Surviving America's Depression Epidemic: How to Find Morale, Energy, and Community in a World Gone Crazy (Chelsea Green, 2007).

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hypocritical and deliberately misleading
Posted by: inverse_agonist on Jul 17, 2009 1:28 AM   
Current rating: 2    [1 = poor; 5 = excellent]
Even though the way stimulants are marketed is shady, and even though they can cause problems for some people, we do not need to panic hysterically. It really doesn't tell you a lot to know that a drug is "amphetamine-like." Sudafed (pseudoephedrine) is "amphetamine-like" and most people reading this have probably taken it and lived. Wellbutrin/Zyban (bupropion) has a "cocaine-like" mechanism of action, but nobody stays up for days strung out on Wellbutrin. We're supposed to be scared because of a quote about similarities in "chemical structure," but it's just fear mongering, taking advantage of the fact that only 1 in 5 people can even explain what a molecule is:

http://www.nsf.gov/statistics/seind02/c7/c7s1.htm

Anything about the long-term effects of stimulants on animals is impossible to interpret without knowing how high the dosages were. Does giving a rat the equivalent of 8 Ritalin pills twice a day tell you something meaningful about giving a person 1 pill twice a day? There are studies done with reasonable dosing regimens, but we have no way of knowing the quality of the studies he's referring to. You're no better than the pharmaceutical companies if you make claims like "3 studies prove this" and you don't actually cite them.

We have known about amphetamine psychosis for a really long time. It happens when people take enormous amounts of amphetamines. If anonymous "researchers at Yale" were giving rhesus monkeys enough amphetamine to cause hallucinations, is this relevant to people taking prescribed doses? Do those doses cause persistent cognitive impairments? Everyone understands that you can drink a beer a day and be fine, but chronic alcoholism is very bad for you. Alcohol is a drug, just like amphetamine. The same principle applies.

Next is the really scary stuff: all of our children will die of Parkinson's disease! Lower levels of dopamine and decreased expression of dopamine transporters are a mechanism of tolerance, so this is not highly surprisong or alarming in and of itself. SSRIs downregulate the serotonin transporter and that in itself isn't cause for concern. Using too many amphetamines is bad for you and probably neurotoxic. That still doesn't mean you're going to get Parkinson's disease. You must lose ~80% or more of your dopamine neurons before you begin to show symptoms of Parkinson's disease. We have a lot of dopamine "in reserve."

The study in humans referred to is probably this one (Bruce Levine is sloppy with references, so we'll have to assume):

http://www.ncbi.nlm.nih.gov/pubmed/16620991

They called Parkinson's patients on the phone and asked them and their spouses about lifetime amphetamine exposure. The spouses were the controls. A greater proportion of Parkinson's patients had used amphetamines! Yes, but men get Parkinson's disease more often than women do, and men use drugs more than women do. How much amphetamine had the Parkinson's group used compared to gender-matched controls? We don't know, because they didn't use gender-matched controls.

Anyone who has ever been outside knows there are massive problems with parenting in the United States, and that ADHD drugs are overprescribed. That doesn't mean Bruce Levine is somehow a more reliable source of information than the companies he's criticizing. He ends with a reference to his book, complete with year of release and publishing company, but doesn't do the same for any studies he's writing about. He's not even really writing about them. He's writing about what someone at Scientific American wrote about them. He's even helpfully included a link to a site where we can buy his books!

This is basically a guy who criticizes companies for conflicts of interest and spinning data while spinning data to drum up book sales.

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» you are misleading... Posted by: mgmyers79
Good luck getting our cornfed electorate to wake up and learn.
Posted by: JenniferBedingfield on Jul 17, 2009 2:35 AM   
Current rating: 4    [1 = poor; 5 = excellent]
Besides, that'll "pass" a drug test while marijuana won't !

[« Reply to this comment] [Post a new comment »] [Rate this comment: 1 - 2 - 3 - 4 - 5]

Don Quixote
Posted by: Don Quixot on Jul 17, 2009 3:03 AM   
Current rating: 4    [1 = poor; 5 = excellent]
What is a Pharma-corp CEO first duty? Profit generation. How many people sitting in the Board meetings dare to oppose the means?

[« Reply to this comment] [Post a new comment »] [Rate this comment: 1 - 2 - 3 - 4 - 5]

Brings back bad memories
Posted by: pure_genius on Jul 17, 2009 3:40 AM   
Current rating: 4    [1 = poor; 5 = excellent]
I have Asperger's, a high functioning form of Autism. Because it was not added to the DSM until 1994, I was misdiagnosed with everything from ADHD from Anti-Social Personality Disorder.

When I was diagnosed with ADHD at age 12, I was prescribed Ritalin. Within a month I began exhibiting severe behavioral problems. While these changes should have been attributed to the medication, I was hospitalized and diagnosed with Conduct Disorder and Oppositional Defiant Disorder. Not long after that I began experiencing severe mood disturbances. I was diagnosed with Bi-Polar Disorder and placed on Lithium. I became so deeply depressed by it that I swallowed an entire bottle. I was hospitalized for a second time and placed on every class of antidepressant during my three month stay.

During my adolescence I was prescribed at least one drug in every class of psychotropics and in most cases more than one. The result has been a marked decrease in cognitive function. My performance IQ dropped from 130 to 85 and my total IQ dropped to 100 from 140. For reasons that my doctors cannot explain my verbal IQ only dropped 10 points. I also have severe permanent Tardive Dyskinesia. A movement disorder caused by the antipsychotics Haldol and Risperdal. The latter was supposed to be formulated specifically not to cause the condition.

Although everyday is a struggle, I must consider myself lucky. Dozens of my fellow patients attempted suicide while on Prozac and I witnessed two succeed. Before I started the drugs the worst thing I ever did was skip school a few times. While at the peak of this experience and on 8 different drugs a day, I attempted to kill two other patients.

I wish more people understood while there is the unachievable goal of a drug-free America many children are being forced onto substances that are just as bad or far worse than any illicit drug.

[« Reply to this comment] [Post a new comment »] [Rate this comment: 1 - 2 - 3 - 4 - 5]

» RE: Brings back bad memories Posted by: Hechicera
» RE: Brings back bad memories Posted by: pure_genius
» RE: Brings back bad memories Posted by: Hechicera
» RE: Brings back bad memories Posted by: pure_genius
» me too! Posted by: re:mcd.'s
drug dealers
Posted by: shine0854 on Jul 17, 2009 3:51 AM   
Current rating: 5    [1 = poor; 5 = excellent]
The pharma companies are the real traffickers in our society and bribing doctors to market their products is the same exact maneuvering that is done in the illegal drug market. The only difference is they operate legally with their massive lobbying interests and political connections.
What is wrong with this picture??

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CHILDREN ARE A SPECIAL POPULATION
Posted by: drricklippin on Jul 17, 2009 3:52 AM   
Current rating: 5    [1 = poor; 5 = excellent]
We need to be extra careful and conservative before we put our children on meds- especially chronic meds.

The legal "drug pushers" (Big PhRMA) aren't careful enough with any of us but they need to be extra careful with our nation's children.

A while back they even declared a diagnosis and treatment for teenagers who sleep late into the morning or early afternoon. That is just one bizarre example of disease mongering for profit.

Dr. Rick Lippin
Southampton,Pa

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My Pediatrician is Not a Pusher!
Posted by: byeager on Jul 17, 2009 5:31 AM   
Current rating: 4    [1 = poor; 5 = excellent]
My son has taken one of the "amphetamine-like" drugs mentioned here every day for the past 5 years, and he is certainly not addicted to it. The prescription comes from our very thoughtful and pharmaceutically conservative pediatrician, but the person who sent us to get it was his second grade teacher. She wasn't interested in dealing with 7 year olds who didn't hang on her every word. Let's be clear that an "ADHD" brain (nobody likes that label--I think of it as a learning style) is NOT adapted to public education that is driven by standardized testing. My son has problems with executive function, including working memory and switching focus on command. Medication HELPS him focus in school, although it certainly doesn't solve all his problems. Obviously, if it didn't help him, we wouldn't give it to him. If we had the luxury of switching out of public school into a less traditional classroom, we'd do it. Since we can't afford that, we have to weigh the lightly-documented long-term effects of the medication against the certain effects of wrecked self-image for a smart kid who can't perform as his teachers expect him to. Levine needs to note the role that No Child Left Behind has played in this conspiracy.

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» hold it!!! Posted by: ellie
» RE: hold it!!! Posted by: snax
» RE: hold it!!! Posted by: ellie
» Great comment, Ellie! Posted by: Centavo
» RE: hold it!!! Posted by: docted
PurduePharma gets a woody
Posted by: weathered on Jul 17, 2009 7:16 AM   
Current rating: 4    [1 = poor; 5 = excellent]
Indict the Sacklers, they've known for well over a decade the destruction of addiction their 24hr. release drugs have wrought.

[« Reply to this comment] [Post a new comment »] [Rate this comment: 1 - 2 - 3 - 4 - 5]

Just Be Careful...Parents
Posted by: picket on Jul 17, 2009 8:13 AM   
Current rating: 4    [1 = poor; 5 = excellent]
When the child becomes of age and no longer has the supervision of caring parents a brain on Adderall needs special care re the addictive qualities of this legal amphetamine.

When away from the help necessary in getting the LEGAL prescription what happens to the young person no longer helped by parent drug plans? Every effort is needed before the young person, maybe now in college, goes the IllEGAL route and finds a jail bed eagerly waiting, thus becoming what society likes to call drug addicts.

Not to mention any names but Adderall has the side effect of being an appetite suppressant and I remember a Hollywood star[very thin] who went to jail and probably had withdrawal from the Adderall she was on, probably prescribed for another reason. Her parents had the connections and wealth to have her doctor take her out of jail and assist in the medical problem resulting from the amphetamine, and then she was returned to jail.

Most people never have this ability to help their children, once they become young adults and are out on their own. Most young people do not have the $$$ to keep regular MD appointments and to be able to afford the RX after leaving home.

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» RE: Just Be Careful...Parents Posted by: Hechicera
» RE: Just Be Careful...Parents Posted by: Hechicera
"drug problem"
Posted by: wireup on Jul 17, 2009 8:22 AM   
Current rating: 4    [1 = poor; 5 = excellent]
And people wonder WHY we have drug problem in this country? This would be a joke if it wasn't so serious!

We have a "drug problem" because Pharma pushes drugs. They are the world's biggest drug pushers.

And people in this country are too damned stupid to understand this.

DRUGS are not generally necessary. There are all sorts of other things that MAKE them unnecessary.

I don't have any drugs in my house - not even aspirin - and will ALWAYS seek what are considered to be alternatives and use them, whenever possible. Like surgery, drugs are the last thing I turn to when I am sick. Only when what are considered to be alternatives do NOT work do I then turn to drugs which - for me - ARE the alternatives.

In this crazy society, drugs have become main stream. Everything else is alternative. Absolutely INSANE!

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» RE: "drug problem" Posted by: docted
» RE: "drug problem" Posted by: VTy
Useful Article
Posted by: Gravitas on Jul 17, 2009 9:04 AM   
Current rating: 4    [1 = poor; 5 = excellent]
This was an excellent article! I have a friend who ghostwrites for pharma. So to put it more directly, she manufactures the "evidence" in evidence based medicine. Whatever study results pharma wants, pharma gets, one way or another. Anyone defending pharma these days either works for them, or is to afraid to think for themselves.

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Iatrogenesis
Posted by: sunnywater on Jul 17, 2009 9:44 AM   
Current rating: 4    [1 = poor; 5 = excellent]
Iatrogenesis is the third leading cause of death in the US.

Causes of iatrogenesis include medical error, negligence, and the adverse effects or interactions of prescription drugs. In the United States, from 120,000 to 225,000 deaths per year may be attributed in some part to iatrogenesis.

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» RE: Iatrogenesis Posted by: wiegie
Get off Perscription Meds!!
Posted by: Johnism on Jul 17, 2009 12:17 PM   
Current rating: 4    [1 = poor; 5 = excellent]
I absolutely loathe big pharma the ultimate drug pushers. Children should not be taking daily medication. I don't believe that 99% of people should be taking daily meds but especially not children.

Hey parents learn to interact with your kids instead of doping them up so they calm down and stare at a TV for 6 hours a night.

I used to work for a medicare supplement provider and would watch seniors bring out shoe boxes full of pills they took on a daily basis. Taking 30 pills a day cannot be healthy and probably shortened their lives not increased it.

Give the seniors some pot and get them off the hard stuff.

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Very sad and very ridiculous...
Posted by: bnvasquez on Jul 17, 2009 2:44 PM   
Current rating: 4    [1 = poor; 5 = excellent]
I'm a psych major and I have learned a bit about the controversy regarding pharm companies (especially with children who are diagnosed with ADHD) I personally feel it's disgusting and I know that when I do get a PhD in clinical psych, I will not be one of the supporters of pharm companies (even though clinical psychologists don't prescribe meds...still.) I want to focus on therapy with recommending medication as the last resort. It's really sad to hear that professionals are taking advantage of their patients and prescribing unnecessary meds that have long-term effects. Giving these meds to children in high dosages and sometimes at all can really affect development. Children's brains are not programmed to handle all kinds of medication, this is why we have to be careful. When it's with adults it's different, and even then there are still precautions with dosages. You cannot compare a child's brain with an adult brain with all the scientific evidence out there.

I personally would get another opinion if the psychiatrist wants to get you or your kid on drugs right away. They probably do have a special kind of relationship with pharm companies...just be careful.

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Just another hatchet-job on Biedermann by just another axe-grinder
Posted by: docted on Jul 17, 2009 3:00 PM   
Current rating: 4    [1 = poor; 5 = excellent]
As the parent of at least one ADD child, and more importantly the HUSBAND of an ADD wife, I can personally vouch for the integrity and professionalism of Joseph Biedermann.

Many years ago, my lovely and highly intelligent wife was notable for having the attention span of a humming-bird. She managed to battle her way through high school and college in spite of this definite deficit by dint of doing triple the work of most of her peers. When we discovered the existence of ADD/ADHD, thanks to a nursing seminar she attended (and experienced an epiphany of "omigawd, that's my kid" followed later by SELF-recognition) we researched "what to do". FORTUNATELY, we were led to Dr. Biederman who did an exhaustive assessment, and subsequently recommend a trial of Ritalin.

The nearly immediate change for the BETTER in her life, and therefore also MY life, and in the life of the child was astounding. She describes it as suddenly being able to hear the radio station she had been TRYING to listen to WITHOUT the previously inescapable STATIC. Suddenly, she could FOCUS. We could actually have a coherent conversation that lasted longer than 37 seconds! The child, by then a college freshman, suddenly found that the classes that had been incomprehensible became *clear* and *comprehensible*. He went on to graduate very nicely.

Those readers who have made it a matter of religion to "not believe in" pharmaceuticals of any kind, even aspirin, are welcome to their beliefs. Just recognize that for MANY of us who do not share in that particular belief system, certain pharmaceuticals are literally life-savers, and sanity-savers. Sure "big pharma" has its negatives. But, as my momma used to say, don't throw out the baby with the bath-water.

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THINK
Posted by: marizara on Jul 17, 2009 7:35 PM   
Current rating: 4    [1 = poor; 5 = excellent]
Don't you find it curious that our government wants to allow the medical community to put all our children on some drug or other, and at the same time wants to forbid us from taking any kind of drugs or vitamins we choose for ourselves? I find that to be extremely disturbing, to say the least. I think there is a problem here with our government that is becoming rather stark in its clarity. We should not be allowing others to determine what we do so easily. Big mistake!

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» RE: THINK Posted by: pure_genius
One question
Posted by: Levon on Jul 20, 2009 10:24 AM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
"A team at the Yale University School of Medicine documented long-lasting behavioral oddities such as hallucinations and cognitive impairment in rhesus monkeys that received injected doses of amphetamines."

How do you tell when a monkey is having a hallucination?

Just ask him?

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CHAOS FIGURE
Posted by: itouch backup on Jul 21, 2009 8:43 PM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
Blu Ray Burner|||MTS Converter For Mac can easily convert MTS files to other popular video/audio formats.

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GENERATION RX Documentary
Posted by: PhilBlank on Jul 22, 2009 8:04 AM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
Seriously folks...do you still doubt that the DSM has little if ANY integrity? All-too-many psychiatrists and researchers are getting away with sleazy behavior and pocketing millions. It's all laid out in the documentary GENERATION RX, which is on Amazon's video-on-demand for a buck or two. Do yourself a favor: watch it—and THEN tell me what you think of this article about ongoing corruption...and the drugging of millions of kids with powerful psychiatric medicines.

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Corruption In The Ivory Towers
Posted by: Triton on Jul 22, 2009 12:16 PM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
Joseph Biederman and Charles Nemeroff are both academic psychiatrists and are on the faculty at prestigious medical schools. The latter was also chairman of the Department of Psychiatry. Both were aware of rules their institutions had regarding the reporting of money received from pharmaceutical companies. Both decided the rules did not apply to them probably because they regard themselves so highly. The case of Biederman is by far the worst as he has played a significant role in the recommendation of drugs which are used in children. Who is willing to believe that his recommendations were not tainted by his dishonesty?

Why are they allowed to teach medical students? They lack credibility and are certainly not positive figures for young physicians to be. We hear much of the honesty found in academic institutions and about how it is so much grander than that seen in government and in business. In fact, it is no better than in any other field. There will always be cheats and frauds who are willing to abuse the system for personal gain.

This has happened at important institutions which are frequently in the lime light. Where else could it be occurring? The Ivory Towers should be more vigilant about the interactions between members of their faculties and pharmaceutical companies as well as the manufacturers of medical devices. Moreover, men like Biederman and Nemeroff should be dismissed.

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leftbank
Posted by: markw4786 on Jul 22, 2009 12:25 PM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
Dr Biederman is not unique. Doctors harm and kill people every day...and their government guardians, the FDA, sanctions these practices. From Big Pharma to the insurance industry to too many doctors to the FDA...let the buyer be ware. Dr Biederman does not belong in civil court rather he should be in criminal court.

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Ethics Committee - a disaster!
Posted by: Pyshnov on Jul 23, 2009 6:30 PM   
Current rating: Not yet rated    [1 = poor; 5 = excellent]
"Ethics" committees have a clear goal - saving the crooks from the jail. The crooks are illiterate, infantile and give bribes. And, only a small part of the so-called "research misconduct" is reported in the mass media.

The "ethical" standards for 5000 scientific journals world-wide published by all main publishing houses are now set by the Committee on Publication Ethics (COPE). These publishers joined COPE with all their 5000 journals last years as members of COPE. This is a tragedy for science.
See this horror:
http://ca.geocities.com/uoftfraud/committee.htm

Michael Pyshnov

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