Synthetic Pot as a Military Weapon? Meet the Man Who Ran the Secret Program

By Martin A. Lee, AlterNet. Posted July 19, 2008.

It was billed as a panel discussion on "the global shift in human consciousness." A half-dozen speakers had assembled inside the Heebie Jeebie Healers tent at Burning Man, the annual post-hippie celebration in Black Rock, Nev., where 50,000 stalwarts braved intense dust storms and flash floods last August. Among the notables who spoke at the early evening forum was Dr. Alexander "Sasha" Shulgin, the Bay Area-based psychochemical genius much beloved among the Burners, who synthesized Ecstasy and 200 other psychoactive drugs and tested each one on himself during his unique, offbeat career.

Sitting on the panel next to Shulgin was an unlikely expositor. Dr. James S. Ketchum, a retired U.S. Army colonel, told the audience, "When Sasha was trying to open minds with chemicals to achieve greater awareness, I was busy trying to subdue people."

Ketchum was referring to his work at Edgewood Arsenal, headquarters of the U.S. Army Chemical Corps, in the 1960s, when America's national security strategists were high on the prospect of developing a nonlethal incapacitating agent, a so-called humane weapon, that could knock people out without necessarily killing anyone. Top military officers hyped the notion of "war without death," conjuring visions of aircraft swooping over enemy territory releasing clouds of "madness gas" that would disorient the bad guys and dissolve their will to resist, while U.S. soldiers moved in and took over.

Ketchum was into weapons of mass elation, not weapons of mass destruction. He oversaw a secret research program that tested an array of mind-bending drugs on American GIs, including an exceptionally potent form of synthetic marijuana. (Most of these drugs had no medical names, just numbers supplied by the Army.) "Paradoxical as it may seem," Ketchum asserted, "one can use chemical weapons to spare lives, rather than extinguish them."

Some of the Burners were perplexed. Was this guy cool or creepy?

Shulgin, a critic of chemical mind-meddling by the military, was wary when he first met Ketchum at a 1993 event honoring the 50th anniversary of the discovery of LSD. But Ketchum is not your typical military bulldozer type. An intelligent, gracious man with a disarming sense of humor, in his own way he has always been a free spirit. He and his wife, Judy, who currently reside in Santa Rosa, became close friends with Sasha and his formidable partner, Ann. They stayed in frequent contact and occasionally socialized together. When the Shulgins invited them to Burning Man, the Ketchums joined the caravan of RVs driving to the desert.

"I'm kind of a Sasha worshipper," Ketchum, who reads neuropharmacology textbooks during his leisure hours, confessed. Tall and lanky, the colonel, now 76, is one of the few people who can actually understand what Shulgin, six years his senior, is talking about when he lectures on the molecular subtleties of psychedelic drugs, waving his arms furiously like a mad scientist. Shulgin took Ketchum under his wing and welcomed him into the fold.

Shulgin wrote the foreword to Ketchum's self-published memoir, Chemical Warfare: Secrets Almost Forgotten, which lifts the veil on the Army's little-known drug experiments and illuminates a hidden chapter of marijuana history. A graduate of Cornell Medical College, Ketchum describes how he was assigned as a staff psychiatrist to Edgewood Arsenal, located 25 miles northeast of Baltimore, in 1961.

"There was no doubt in my mind that working in this strange atmosphere was just the sort of thing that would satisfy my appetite for novelty," Ketchum wrote. Soon he became chief of clinical research at the Army's hub for chemical warfare studies. Although the Geneva Convention had banned the use of chemical weapons, Washington never agreed to this provision, and the U.S. government poured money into the search for a nonlethal incapacitant.

Red Oil

The U.S. Army Chemical Corp's marijuana research began several years before Ketchum joined the team at Edgewood. In 1952, the Shell Development Corporation was contracted by the Army to examine "synthetic cannabis derivatives" for their incapacitating properties. Additional studies into possible military uses of marijuana began two years later at the University of Michigan medical school, where a group of scientists led by Dr. Edward F. Domino, professor of pharmacology, tested a drug called "EA 1476" -- otherwise known as "Red Oil" -- on dogs and monkeys at the behest of the U.S. Army. Made through a process of chemical extraction and distillation, Red Oil, akin to hash oil, packed a mightier punch than the natural plant.

Army scientists found that this concentrated cannabis derivative produced effects unlike anything they had previously seen. "The dog gets a peculiar reaction. He crawls under the table, stays away from the dark, leaps out at imaginary objects and, as far as one can interpret, may be having hallucinations," one report stated. "It would appear even to the untrained observer that this dog is not normal. He suddenly jumps out, even without any stimulus, and barks, and then crawls back under the table."

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Martin A. Lee is the author of Acid Dreams: The Complete Social History of LSD: The CIA, the Sixties, and Beyond. He is writing a social history of marijuana. A version of this article originally appeared in Cannabis Culture.