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Do You Know About the Narcotic Effects of Nutmeg?

By Ibo Nagano, Entheogen Review. Posted June 5, 2009.


Humanity has used nutmeg as a medicine, narcotic, aphrodisiac, dream enhancer and inebriant.
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Nutmeg has been used for thousands of years for multiple purposes. It appears to have a fairly large safety margin for use, although the long-term effects of nutmeg use on the body are not well understood. The biggest known danger from experimentation is dehydration, and the biggest discomfort the resulting hangover. By keeping non-alcoholic/non-caffeinated fluids handy, and drinking often, this hangover (which can otherwise last several days) can likely be avoided.

The most promising aspects of nutmeg seem to be its potential as an anti-depressant and as an aphrodisiac when used in small doses. I have felt improvements in mood and decreases in anxiety with as little as 1/4 tsp in a cup of chocolate, or with one or two cookies from the recipe above. With knowledge of nutmeg's mood-elevating properties going back a thousand years or more, further investigation into the potential of nutmeg as an anti-depressant seems merited.

All in all, nutmeg is a well-rounded little nut. It may be used to brighten your day, to spice up your love life, to flavor your food, to induce vivid dreams, or to just get plain stoned. This seed has been overlooked and misunderstood by many entheophiles, but once one is privy to her secrets she can become a valuable ally

Notes: another secondary source (Shulgin et al. 1967) also citing Truitt et al. 1961, claimed symptoms from 400 mg of myristicin "at least suggestive of psychotropic effects in 6 out of 10 subjects." The original paper by Truitt et al. states that there was a "definite reaction" in each of 4 subjects, and that 2 subjects each had a "questionable reaction."

References:

  • Buhner, S.H. 1998. Sacred and Herbal Healing Beers: The Secrets of Ancient Fermentation. Brewers Publications.
  • C.E.F.S. (Committee of Experts on Flavouring Substances) 2005. Active Principles (Constituents of Toxicological Concern) Contained in Natural Sources of Flavourings. Council of Europe. On-line at www.coe.int.
  • C.S.W.G. (Chemical Selection Working Group) 1997. Summary of Data for Chemical Selection: Myristicin CAS NO. 607-91-0.
  • Duke, J. 2008. "Chemicals in: Myristica fragrans Houtt. (Myristicaceae) Mace, Muskatnussbaum (Ger.), Nutmeg, nogal moscado (Sp.), nuez moscada (Sp.)," Dr. Duke's Phytochemical and Ethnobotanical Databases. Posted at www.ars-grin.gov/duke/, accessed 2/24/08.
  • Fandango, K. 2001. "Recreational Nutmeg Experiment," Erowid ID: 3570. Posted at www.erowid.org/experiences/subs/exp_Nutmeg.shtml, accessed 11/3/07.
  • Forrest, J.E. and R.A. Heacock 1972. "Nutmeg and Mace, The Psychotropic Spices from Myristica fragrans," Lloydia 35(4): 440-449.
  • Haley, A. and M. X 1965. The Autobiography of Malcolm X. Grove Press.
  • Hallstrom, H. and A. Thuvander 1997. "Toxicological Evaluation of Myristicin," Natural Toxins 5: 186-192.
  • Houston, TX 2006. "Question and Answer Session," Traditional and Herbal Remedies: Toxicology and Laboratory Concerns. Posted at www.aacc.org/events/expert_access/2006/toxlab/Pages/default.aspx, accessed 11/3/07.
  • Kalbhen, D.A. 1971. "Nutmeg as a Narcotic," Angewandte Chemie International Edition 10(6): 370-374.
  • Krieg, M.B. 1964. Green Medicine. Rand McNally & Co.
  • Me 2001. "Exactly Like Pot," Erowid. Posted at www.erowid.org/experiences/exp.php?ID=1619, accessed 11/3/07.
  • Morita, T. et al. 2003. "Hepatoprotective Effect of Myristicin from Nutmeg (Myristica fragrans) on Lipopolysaccharide/d-Galactosamine-Induced Liver Injury," Journal of Agricultural and Food Chemistry 51(6): 1560-1565.
  • Oswald, E.O. et al. 1971. "Urinary Excretion of Tertiary Amino Methoxy Methylene-dioxy Propio-phenones as Metabolites of Myristicin in the Rat and Guinea Pig," Biochimica et Biophysica Acta, 244: 322-328.
  • Rtsch, C. 2005. The Encyclopedia of Psychoactive Plants: Ethnopharmacology and Its Applications. Park Street Press.
  • Rtsch, C. and C. Mller-Ebeling 2006. Pagan Christmas: The Plants, Spirits, and Rituals at the Origins of Yuletide. Inner Traditions.
  • Rudgley, R. 1998. The Encyclopedia of Psychoactive Substances. Thomas Dunne Books/St. Martin's Griffin.
  • Salmon, W. 1693. Selapsium The Compleat English Physician: Or, The Druggist's Shop Opened. Matthew Gilliflower/George Sawbridge.
  • Sangalli, B.C. and W. Chiang 2000. "Toxicology of Nutmeg Abuse," Clinical Toxicology 38(6): 671-678.
  • Schultes, R.E. and A. Hofmann 1992. Plants of the Gods: Their Sacred, Healing and Hallucinogenic Powers. Healing Arts Press.
  • Shulgin, A.T. 1967. "The Separation and Identification of the Components of the Aromatic Ether Fraction of Essential Oils by Gas-Liquid Chromatography," Journal of Chromatography 30: 54-61.
  • Shulgin, A. et al. 1967. "The Chemistry and Psychopharmacology of Nutmeg and of Several Related Phenylisoproplamines," in D.H. Efron (ed.) Ethnopharmacologic Search for Psychoactive Drugs, pp. 202-214.
  • Sjoholm, A. et al. 1998. "Acute Nutmeg Intoxication," Journal of Internal Medicine 243: 329-331.
  • Stein, U. et al. 2001. "Nutmeg (Myristicin) Poisoning Report on a Fatal Case and a Series of Cases Recorded by a Poison Information Centre," Forensic Science International 118(1): 87-90.
  • Tajuddin et al. 2003. "Aphrodisiac Activity of 50% Ethanolic Extracts of Myristica fragrans (Nutmeg) and Syzygium aromaticum (Clove) in Male Mice: a comparative study," BMC Complementary Alternative Medicine 3: 6.
  • Tajuddin et al. 2005. " An Experimental Study of Sexual Function Improving Effect of Myristica fragrans Houtt. (Nutmeg)," BMC Complementary Alternative Medicine 5: 16.
  • Truitt, Jr., E.B. et al. 1961. "The Pharmacology of Myristicin, A Contribution to the Psychopharmacology of Nutmeg," Journal of Neuropsych. 2(4): 205-210. [Note: Hallstrom and Thuvander (1997) cite the year of this paper as 1960; while we have not seen a copy of the paper, multiple other references including one in another article by E.B. Truitt give the year as 1961.]
  • Weil, A.T. 1967. "Nutmeg as a Psychoactive Drug," in D.H. Efron (ed.) Ethnopharmacologic Search for Psychoactive Drugs, pp. 188-201.
  • Wilson, B. 1999 (Jan. 29). "Old Spice," New Statesman 128.

Thanks to Erowid for resurfacing this article.


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